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5 HT Receptor/Serotonin Receptor

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5 HT Receptor/Serotonin Receptor

Chemical Structure Cat. No. Product Name CAS No.
SB 203186 hydrochloride Chemical Structure
BCP42428 SB 203186 hydrochloride 135938-17-9
SB203186 is potent 5-HT4 receptor antagonist with high affinity for human atrial 5-HT4 receptors.
Indophagolin Chemical Structure
BCP41936 Indophagolin 1207660-00-1
Indophagolin is a potent autophagy inhibitor with and IC50 value of 140 nM. Indophagolin also shows activity on the purinergic receptors with IC50 values of 2.40 μM, 3.49 μM and 2.71 μM for the P2X1, P2X3 and P2X4 receptors, respectively.
Buspirone Chemical Structure
BCP41132 Buspirone 36505-84-7
Buspirone is an anxiolytic psychotropic drug of the azapirone chemical class. It is primarily used to treat generalized anxiety disorder (GAD). Unlike most drugs predominantly used to treat anxiety, buspirone's pharmacology is not related to benzodiazepines or barbiturates, and so does not carry the risk of physical dependence and withdrawal symptoms for which those drug classes are known.
RS67333 Chemical Structure
BCP40415 RS67333 160845-95-4
RS-67333 is a 5-HT4R partial agonist that shows efficacy at 0.3 and 1.0 mg/kg, ip.
Tesofensine Chemical Structure
BCP37838 Tesofensine 402856-42-2
Tesofensine, an azabicyclo compound, has been found to be a 5-HT receptor inhibitor and could be used in the treatment of obesity.
GR 125743 Chemical Structure
BCP37767 GR 125743 148547-33-5
GR 125743 is a novel 5-HT1B/1D receptor antagonist.
(S)-PF-04995274 Chemical Structure
BCP37093 (S)-PF-04995274 2170558-28-6
PF-04995274 is a 5-HT4 receptor partial agonist with Ki = 0.15 - 0.46 nM for 5-HT4 isoforms a, b, d and e, developed for the treatment of Alzheimer's disease (AD).
Org-12962 Chemical Structure
BCP37028 Org-12962 132834-56-1
Org-12962 is a 5-HT 2C receptor agonist potentially for the treatment of depression.
MK-212 Chemical Structure
BCP37027 MK-212 64022-27-1
MK-212 is a 5HT2C-receptor agonist.
Bromperidol Chemical Structure
BCP36565 Bromperidol 10457-90-6
Bromperidol is a butyrophenone derivative, is a potent and long-acting neuroleptic, used as an antipsychotic in the treatment of schizophrenia.
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