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Angiogenesis/Protein Tyrosine Kinase

Chemical Structure Cat. No. Product Name CAS No.
TPX-0131 Chemical Structure
BCP42131 TPX-0131 2648641-36-3
TPX-0131 is a CNS-penetrant, next-generation ALK inhibitor that has potency against wild-type ALK and a spectrum of acquired resistance mutations, especially the G1202R solvent front mutation and compound mutations, for which there are currently no effective therapies.
Norleual Chemical Structure
BCP41927 Norleual 334994-34-2
Norleual, an angiotensin IV analog, competitively inhibited the binding of HGF to its receptor c-Met in mouse liver membranes. It is also an AT4 receptor antagonist, which disrupts LTP stabilization.
AZ Dyrk1B 33 Chemical Structure
BCP41848 AZ Dyrk1B 33 1679330-37-0
AZ Dyrk1B 33 is a potent and selective ATP-competitive Dyrk1B kinase inhibitor.
CNX-500 Chemical Structure
BCP40963 CNX-500 1202758-21-1
CNX-500 is a probe consisting of a covalent Btk inhibitor chemically linked to biotin.
CSF1R-IN-2 Chemical Structure
BCP40929 CSF1R-IN-2 2271119-26-5
TPX-0022, also known as CSF1R-IN-2, is an orally bioavailable multi-targeted kinase inhibitor with a novel three-dimensional macrocyclic structure that inhibits the MET, CSF1R (colony stimulating factor 1 receptor) and SRC kinases.
SHR0302 Chemical Structure
BCP34833 SHR0302 1445987-21-2
SHR0302 is a novel potent JAK inhibitor, blocking JAK/STAT3 signaling, suppressing proliferation, migration and collagen production, and inducing the apoptosis of hepatic stellate cells.
Gilteritinib hemifumarate Chemical Structure
BCP40569 Gilteritinib hemifumarate 1254053-84-3
Carotegrast Chemical Structure
BCP40366 Carotegrast 401904-75-4
Carotegrast is an anti-inflammatory agent.
DS-1206b Chemical Structure
BCP40272 DS-1206b 1855860-24-0
DS-1206b is a selective and potent AXL kinase inhibitor with IC50 of 1.3?nM.
XL-092 Chemical Structure
BCP40284 XL-092 2367004-54-2
XL092 is an investigational, next-generation oral TKI that targets VEGF receptors, MET, AXL, MER and other kinases implicated in the growth and spread of cancer.
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