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CDK

Chemical Structure Cat. No. Product Name CAS No.
CDK4 inhibitor compound 12 Chemical Structure
BCP41586 CDK4 inhibitor compound 12 2105956-77-0
CDK4 inhibitor compound 12 is a novel inhibitor of CDK4 with the activity 97 μM.
KB-0742 Chemical Structure
BCP41310 KB-0742 2416873-83-9
KB-0742 is an orally bioavailable, selective CDK9 inhibitor with potent anti-tumor activity in CRPC models.
BSJ-4-116 Chemical Structure
BCP40986 BSJ-4-116 2519823-34-6
BSJ-4-116 selectively degraded CDK12 as assessed through quantitative proteomics.
YKL-5-124 Chemical Structure
BCP40930 YKL-5-124 1957203-01-8
YKL-5-124 is a potent and highly selective covalent CDK7 inhibitor which causes arrest at the G1/S transition and inhibition of E2F-driven gene expression.
GW805758X Chemical Structure
BCP38035 GW805758X GW805758X
GW805758X is a potent inhibitor of CDK-4 which demonstrates enzyme selectivity against VEGFR-2 and GSK3β.
FIT-039 Chemical Structure
BCP37988 FIT-039 1113044-49-7
FIT-039 is a potent, selective CDK9 inhibitor with IC50 of 5.8 uM for CKD9/cyclin T1, suppresses the replication of HSV-1 (IC50=0.69 uM).
CDKI-73 Chemical Structure
BCP37660 CDKI-73 1421693-22-2
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM. It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM). The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.
BSJ-03-123 Chemical Structure
BCP36852 BSJ-03-123 2361493-16-3
BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
PROTAC CDK9 Degrader-1 Chemical Structure
BCP36814 PROTAC CDK9 Degrader-1 2118356-96-8
PROTAC CDK9 Degrader-1 is a selective CDK9 degrader.
THAL-SNS-032 Chemical Structure
BCP36024 THAL-SNS-032 2139287-33-3
THAL-SNS-032 is a selective CDK9 degrader. THAL-SNS-032 consists of a CDK-binding SNS-032 ligand linked to a thalidomide.
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