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Phospholipase

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Phospholipase

Chemical Structure Cat. No. Product Name CAS No.
ML298 Chemical Structure
BCP37987 ML298 1426916-02-0
ML-298 is a potent inhibitor of phospholipase D2 (PLD2) displaying selectivity for PLD2 over PLD1 with IC50 values of 355 and 20000 nM, respectively.
ML349 Chemical Structure
BCP37902 ML349 890819-86-0
ML 349 is a lysophospholipase 2 inhibitor with IC50 value of 144 nM.
ML-299 Chemical Structure
BCP37841 ML-299 1426916-00-8
ML-299 is a dual PLD1/2 inhibitor (PLD1 IC50 = 6 nM, PLD2 IC50 = 20 nM).
YM 26734 Chemical Structure
BCP37836 YM 26734 144337-18-8
YM-26734 is an inhibitor of rabbit platelet sPLA2.
Aacocf3 Chemical Structure
BCP33391 Aacocf3 149301-79-1
AACOCF3 is a fatty acid derivative that is arachidonic acid in which the OH part of the carboxy group has been replaced by a trifluoromethyl group
CAY10650 Chemical Structure
BCP32595 CAY10650 1233706-88-1
CAY10650 is a potent cPLA2a inhibitor, demonstrating strong anti-inflammatory effects.
N-(p-amylcinnamoyl) Anthranilic Acid Chemical Structure
BCP30845 N-(p-amylcinnamoyl) Anthranilic Acid 110683-10-8
N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker. N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is also an effective reversible inhibitor of calcium-activated chloride channels, has potential to treat arrhythmia.
CAY10594 Chemical Structure
BCP30751 CAY10594 1130067-34-3
CAY10594 is a potent PLD2 inhibitor, both in vitro (IC50 = 140 nM) and in cells (IC50 = 110 nM). It is also effective as a PLD1 inhibitor at higher concentrations (IC50 = 5.1 μM in vitro, 1.0 μM in cells). CAY10594 strongly inhibits the invasive migration of breast cancer cells in transwell assays, suggesting that PLD might be a useful target in blocking tumor cell invasion.
Phospholipase?A2 Chemical Structure
BCP29853 Phospholipase?A2 9001-84-7
Phospholipases A2 (PLA2s) EC 3.1.1.4 are enzymes that cleaves fatty acid in position two of phospholipids, hydrolyzing the bond between the second fatty acid “tail” and the glycerol molecule.
Varespladib sodium Chemical Structure
BCP20960 Varespladib sodium 172733-42-5
Varespladib Sodium is an intravenously administered inhibitor of secretory phospholipase A2 (sPLA2) with orphan drug designation.
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