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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
MK-0941 Chemical Structure
BCP42876 MK-0941 752240-01-0
MK-0941 is an orally active and allosteric glucokinase activator, has potential in the treatment of type 2 diabetes.
LXRβ agonist-2 Chemical Structure
BCP42686 LXRβ agonist-2 1949801-52-8
LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM.
ABT-100 Chemical Structure
BCP42635 ABT-100 450839-40-4
ABT-100 is a potent, highly selective and orally active farnesyltransferase inhibitor. ABT-100 inhibits cell proliferation (IC50s of 2.2 nM, 3.8 nM, 5.9 nM, 6.9 nM, 9.2 nM, 70 nM and 818 nM for EJ-1, DLD-1, MDA-MB-231, HCT-116, MiaPaCa-2, PC-3, and DU-145 cells, respectively), increases apoptosis and decreases angiogenesis. ABT-100 possesses broad-spectrum antitumor activity.
Shepherdin Chemical Structure
BCP42633 Shepherdin 861224-28-4
Shepherdin makes extensive contacts with the ATP pocket of Hsp90, destabilizes its client proteins, and induces massive death of tumor cells by apoptotic and nonapoptotic mechanisms.
CDD3505 Chemical Structure
BCP42511 CDD3505 173865-33-3
CDD3505 is used for elevating high density lipoprotein cholesterol (HDL) by inducing hepatic cytochrome P450IIIA (CYP3A) activity.
KEA1-97 Chemical Structure
BCP42477 KEA1-97 2138882-71-8
KEA1-97 is a small molecule that disrupts the interaction of thioredoxin with caspase 3.
AG-636 Chemical Structure
BCP40942 AG-636 1623416-31-8
AG-636 is a potent, reversible, selective and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM.
CASP3 Activator-1541 Chemical Structure
BCP41874 CASP3 Activator-1541 1100353-03-4
CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.
BMS-986242 Chemical Structure
BCP41750 BMS-986242 1923844-48-7
BMS-986242 is a novel Potent, Selective Inhibitor of Indoleamine-2,3-dioxygenase 1 (IDO1).
XEN723 Chemical Structure
BCP41701 XEN723 1072803-08-7
XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively.
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