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Proteasome

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Proteasome

Chemical Structure Cat. No. Product Name CAS No.
Calpain Inhibitor XII Chemical Structure
BCP40190 Calpain Inhibitor XII 181769-57-3
Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 with Ki of 19 nM.
TCH-165 Chemical Structure
BCP37629 TCH-165 1446350-60-2
TCH-165 is a small molecule modulator of proteasome assembly, which increases 20S levels and facilitates 20S-mediated protein degradation.
MG101 Chemical Structure
BCP28014 MG101 110044-82-1
MG-101 is a potent inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively.
MarizoMib Chemical Structure
BCP13082 MarizoMib 437742-34-2
Marizomib, also known as ML 858, NPI-0052 and Salinosporamide A, is a potent and selective 20S proteasome inhibitor from natural origin.
Lactacystin Chemical Structure
BCP13243 Lactacystin 133343-34-7
Lactacystin is a specific and an irreversible inhibitor of proteasome with IC50 value of 4.8 μM.
(R)-MG-132 Chemical Structure
BCP28290 (R)-MG-132 1211877-36-9
MG132 is a potent 20S proteasome inhibitor (IC50 = 0.22 nM). Exhibits cytostatic and cytotoxic effects in tumor cells in vitro.
PI-1840 Chemical Structure
BCP28597 PI-1840 1401223-22-0
PI-1840 is a potent and selective inhibitor for chymotrypsin-like (CT-L) (IC50 value = 27 ± 0.14 nM) over trypsin-like and peptidylglutamyl peptide hydrolyzing (IC50 values >100 μM) activities of the proteasome.
Ixazomib citrate Chemical Structure
BCP16600 Ixazomib citrate 1239908-20-3
MLN2238 rapidly hydrolyzes to MLN2238, which is a selective, orally bioavailable, second-generation proteasome inhibitor, inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 value of 3.4 nM (Ki of 0.93 nM), and also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites with IC50 of 31 and 3500 nM, respectively.
Cysteine Protease inhibitor Chemical Structure
BCP11075 Cysteine Protease inhibitor 921625-62-9
Cysteine Protease inhibitor is a inhibitor of cysteine protease.
Gabexate mesylate Chemical Structure
BCP13557 Gabexate mesylate 56974-61-9
Gabexate Mesylate is a Factor X inhibitor.
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